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10.1016/j.jtice.2021.02.016 20 DaiQ.LiQ.GaoH.YaoL.LinZ.LiD.et al (2021)

When a carboxylic acid (pH 4) is added to a solution containing an amine (R-NH 2 ), an acid-base reaction quickly occurs, resulting in formation of the ammonium salt R-NH 3 (+) with a pK a of about 9